Premotor Phase of Early Parkinson Disease (review)
- VernacularTitle:帕金森病运动前期研究进展
- Author:
Shujun JIAO
;
Hong YUAN
;
Liwu LIANG
- Publication Type:Journal Article
- Keywords:
Parkinson disease, premotor phase, nonmotor symptoms, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2011;17(1):42-44
- CountryChina
- Language:Chinese
-
Abstract:
Clinical, neuroimaging, and pathologic studies suggested that a variety of nonmotor symptoms, such as olfactory dysfunction, dysautonomia, and mood and sleep disorders, can precede the typic motor features of Parkinson disease (PD) by years and, perhaps, even decades. The period when these symptoms arise can be referred as the premotor phase of the disease. This paper reviewed the conception, clinical manifestation, pathology, diogose of the premotor phase of early Parkinson disease.
