Comparative analysis of domestic classification management list for clinical use of antibiotics versus WHO AWaRe classification list of antibiotics
- VernacularTitle:国内抗菌药物临床应用分级管理目录与WHO抗菌药物AWaRe分级目录的对比分析
- Author:
Yaoyao YANG
1
;
Kexin LING
1
;
Xi ZHANG
1
;
Kexin DU
1
;
Wanmeng ZHANG
1
;
Lin HU
1
;
Bo ZHENG
2
;
Xiaodong GUAN
1
;
Wushouer HAISHAERJIANG
1
,
3
;
Luwen SHI
1
Author Information
1. Dept. of Pharmacy Administration and Clinical Pharmacy，School of Pharmaceutical Sciences，Peking University，Beijing 100191，China
2. Institute of Clinical Pharmacology，Peking University First Hospital，Beijing 100191，China
3. International Research Center for Medicinal Administration，Peking University，Beijing 100191，China
- Publication Type:Journal Article
- Keywords:
antibiotics;
classification management;
AWaRe classification list;
China;
World Health Organization
- From:
China Pharmacy
2022;33(24):2945-2951
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To provide reference and suggestions for dynamic adjustment of classification management lists for clinical use of antibiotics and the promotion of rational use of antibiotics. METHODS The latest version of provincial classification management lists for clinical use of antibiotics were aggregated into the “national list”， which was compared with 2021 WHO AWaRe classification list of antibiotics （hereinafter referred as to “AWaRe classification list”） to make a descriptive statistical analysis about the number of different classes of antibiotics in the two lists and their differences. RESULTS Based on the different classification principles， 262 kinds of antibiotic preparations in the national list were classified into non-restricted （84）， restricted （83） and highly-restricted classes （95）， and 258 kinds in the AWaRe classification list were classified into access （87）， watch （142） and reserve classes （29）； 182 kinds of antibiotic preparations were both included in the two lists. In the national list， among the non-restricted antibiotic preparations， 36 kinds belonged to access class， 30 belonged to watch class and 1 belonged to reserve class； among restricted antibiotic preparations， 7 belonged to access class， 46 kinds belonged to watch class and 3 belonged to reserve class； among highly-restricted antibiotic 82805019。E-mail：yyy211anne@163.com preparations， 9 belonged to access class， 35 belonged to watch class and 15 kinds belonged to reserve class. Among them， 91 kinds of antibiotic preparations were not recommended by WHO （20 kinds） or not included in the AWaRe classification list （71 kinds）. CONCLUSIONS The classification methods of two lists are different in classification principles and grading of some similar drugs. The classification management list of antibiotics is one of the key points of antibiotics management， more research is needed in the future to provide sufficient evidence for optimizing antibiotics classification management.
