Evaluation of leptin, interleukin-1 beta and tumor necrosis factor alpha in serum of malaria patients as prognostic markers of treatment outcome
10.12980/APJTB.4.201414B11
- Author:
Mariam Abdulrhman AL-FADHLI
1
;
Mohammad Ahmed SARAYA
1
;
Mohammad Ahmed SARAYA
2
;
Jafar Abdulrida QASEM
3
Author Information
1. Department of Medicine, Infectious Disease Hospital, Ministry of Health
2. Department of Tropical Medicine, Faculty of Medicine, Zagazig University
3. Department of Applied Medical Sciences, College of Health Sciences, Public authority for Applied Education and Training
- Publication Type:Journal Article
- Keywords:
IL-1;
Kuwait;
Leptin;
Malaria;
Tumor necrosis factor alpha (TNFα)
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(6):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze serum leptin levels in patients with malaria falciparum and compare them with healthy controls and correlate with development and outcome of malaria infection. Methods: Sixty cases of malaria falciparum were included in this study as patients. Thirty healthy individuals of comparable age, racial and body mass index were taken as controls. All patients were diagnosed by clinical picture and the presence of malaria parasites in blood film. Estimation of liver function test, kidney function test, complete blood count, fasting blood sugar, fasting serum insulin, pro-inflammatory cytokine tumor necrosis factor alpha (TNFα) and interleukin 1 (IL1), estimation of morning serum leptin and calculation of body mass index (kg/m
