Proteomics analysis of antimalarial targets of Garcinia mangostana Linn
10.12980/APJTB.4.2014APJTB-2014-0043
- Author:
Wanna CHAIJAROENKUL
1
;
Artitiya THIENGSUSUK
1
;
Kesara NA-BANGCHANG
1
;
Kanchana RUNGSIHIRUNRAT
2
;
Stephen Andrew WARD
3
Author Information
1. Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus)
2. College of Public Health Sciences, Chulalongkorn University
3. Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, University of Liverpool
- Publication Type:Journal Article
- Keywords:
Garcinia mangostana Linn;
Malaria;
Proteomics
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(7):515-519
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate possible protein targets for antimalarial activity of Garcinia mangostana Linn. (G. mangostana) (pericarp) in 3D7 Plasmodium falciparum clone using 2-dimensional electrophoresis and liquid chromatography mass-spectrometry (LC/MS/MS). Methods: 3D7 Plasmodium falciparum was exposed to the crude ethanolic extract of G. mangostana Linn. (pericarp) at the concentrations of 12μg/mL (IC
