Susceptibility of microorganism to selected medicinal plants in Bangladesh
10.12980/APJTB.4.201414B362
- Author:
Md. Mustahsan BILLAH
1
;
Mohammad Salim HOSSAIN
1
;
Sujan BANIK
1
;
Golam Sarwar RAJU
1
;
Zannatul NAIM
2
Author Information
1. Department of Pharmacy, Noakhali Science and Technology University
2. Department of Pharmacy, Atish Dipankar University of Science and Technology
- Collective Name:Department of Pharmacy, Noakhali Science and Technology University;Department of Physiology, Biochemistry and Pharmacology, Chittagong Veterinary and Animal Sciences University;Department of Physiology, Biochemistry and Pharmacology, Chittagong Veterinary and Animal Sciences University
- Publication Type:Journal Article
- Keywords:
Antibacterial activity;
Antifungal activity;
Percentage of inhibition;
Susceptibility;
Zone of inhibition
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(11):911-917
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze in-vitro antimicrobial activities of some ethno-pharmacologically significant medicinal plants (methanol extract) against the pathogenic microorganisms (Escherichia coli, Salmonella spp., Bacillus cereus, Staphylococcus aureus, Aspergillus niger and Candida albicans). Methods: The disc diffusion method was applied for antibacterial test and the poisoned food technique was applied for antifungal test. Results: The methanol extract of Terminalia chebula (bark), Phyllanthus acidus (fruits), Sarcochlamys pulcherrima (leaves) and Abelmoschus esculentus (fruits) had significant in vitro antibacterial activity angainst the entire test samples in comparison to standard drug ciprofloxacin. Most of the plant extracts showed low activity against Gram negative bacteria while potential activity against Gram positive bacteria. The antifungal activities of methanol extracts of these plants and standard drug griseofulvin were determined against two pathogenic fungi, and Polygonum lapathifolium (leaves) and Cinnamomum tamala (leaves) showed maximum activity, while Erioglossum rubiginosum (leaves) showed no antifungal activity. Conclusions: Further chemical and pharmacological investigations are required to identify and isolate chemical constituents responsible for these potential bioactivities and thus to determine their full spectrum of efficacy.