Fungi as chemical industries and genetic engineering for the production of biologically active secondary metabolites
10.12980/APJTB.4.2014APJTB-2014-0230
- Author:
Abid Ali KHAN
1
;
Umar FAROOQ
1
;
Abid Ali KHAN
2
;
Nafees BACHA
2
;
Bashir AHMAD
2
;
Ghosia LUTFULLAH
2
;
Russell John COX
3
Author Information
1. Department of Chemistry, COMSATS Institute of Information Technology
2. Centre of Biotechnology and Microbiology, University of Peshawar
3. School of Chemistry, University of Bristol
- Publication Type:Journal Article
- Keywords:
Chemical biology;
Fungi;
Microbiology;
Molecular genetics;
Natural products
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(11):859-870
- CountryChina
- Language:Chinese
-
Abstract:
Fungi is somewhere in between the micro and macro organisms which is a good source of producing biologically active secondary metabolites. Fungi have been used as tool for producing different types of secondary metabolites by providing different nutrients at different laboratory conditions. The fungi have been engineered for the desired secondary metabolites by using different laboratory techniques, for example, homologous and heterologous expressions. This review reported how the fungi are used as chemical industry for the production of secondary metabolites and how they are engineered in laboratory for the production of desirable metabolites; also the biosynthetic pathways of the bio-organic-molecules were reported.
