Antioxidant, antimicrobial, cytotoxic and analgesic activities of ethanolic extract of Mentha arvensis L.
10.12980/APJTB.4.2014C1298
- Author:
Nripendra Nath BISWAS
1
;
Nripendra Nath BISWAS
2
;
Subarna SAHA
2
;
Mohammed Khadem ALI
3
Author Information
1. School of Chemistry, University of New South Wales
2. Pharmacy Discipline, Life science school, Khulna University
3. Department of Biotechnology and Genetic Engineering, Life Science School, Khulna University
- Publication Type:Journal Article
- Keywords:
Analgesic;
Antibacterial;
Antioxidant;
Cytotoxic;
Mentha arvensis L.
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(10):792-797
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate potential antioxidant, antimicrobial, cytotoxic and analgesic activities of ethanolic extract of Mentha arvensis L. in different in vivo and in vitro experimental models. Methods: In vitro DPPH radical scavenging assay was used to evaluate the antioxidant activity of the plant extract. In vivo analgesic activity was carried out by acetic acid-induced writhing test in Swiss albino mice. All studies in mice were undertaken at the doses of 250 and 500 mg/kg body weight. Antibacterial activity was studied by disk diffusion assay against some Gram-positive and Gram-negative bacterial strains. Brine shrimp lethality assay was used to investigate cytotoxicity effects of the plant extract. Results: The extract showed free radical scavenging activity in the DPPH assay (IC
