Genetic diversity and gene structure of mitochondrial region of Anopheles minimus (Diptera: Culicidae) - major malaria vector of North east India
- Author:
Prafulla DUTTA
1
;
Siraj Ahmed KHAN
1
;
Rashmee TOPNO
1
;
Pritom CHOWDHURY
1
;
Mayuri BAISHYA
1
;
Purvita CHOWDHURY
1
;
Jagadish MAHANTA
1
Author Information
- Publication Type:Journal Article
- Keywords: Anopheles minimus; Cytochrome oxidase II; Haplotype; Mutation; Substitution
- From: Asian Pacific Journal of Tropical Medicine 2014;7(12):952-955
- CountryChina
- Language:Chinese
- Abstract: Objective: To depict mitochondrial genetic variation for the first time among Anopheles minimus (. An.minimus) (Diptera: Culicidae) species from two malaria endemic states of NE India. Methods: Phylogeographic analysis was carried at 9 out of 12 sites of An.minimus confirmed malaria endemic places. Results: All sequences were Adenine-Thymine rich regions. Transitions were observed in 6 sequences where 5 mutations were synonymous substitutions and in 1 case non synonymous mutation was observed. Three distinct clusters of haplotypes were generated. Haplotype diversity and low nucleotide diversity were studied. Overall negative values obtained from Tajima's D test and Fu'sF
