Evaluation of antioxidant, in vitro cytotoxicity of micropropagated and naturally grown plants of Leptadenia reticulata (Retz.) Wight & Arn.-an endangered medicinal plant
10.1016/S1995-7645(14)60244-3
- Author:
Sudipta Kumar MOHANTY
1
;
Anuradha MANIYAM
1
;
Kumaraswamy MALAPPA
2
;
Anuradha MANIYAM
2
;
Ashok GODAVARTHI
3
;
Balasubramanya SUBBANARASIMAN
4
;
Anuradha MANIYAM
4
Author Information
1. Department of Biotechnology, Acharya Nagarjuna University
2. Padmashree Institute of Management and Sciences
3. Radiant Research Pvt. Ltd No: 2/36, Shreyas Arcade
4. Rishi Foundation
- Publication Type:Journal Article
- Keywords:
Antioxidant;
Cytotoxicity;
Leptadenia reticulata;
Micropropagation
- From:
Asian Pacific Journal of Tropical Medicine
2014;7(S1):S267-S271
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the antioxidant and anti proliferative potential of different solvent extract of micropropagated and naturally grown plants of Leptadenia reticulata against various cancer cell lines. Methods: In this study different extract were tested for cytotoxicity against human breast adenocarcinoma cell line MCF-7, human colon adenocarcinoma grade II cell line HT-29 and non cancer skeletal muscle cell line L6 through 3-(4, 5-dimethyl thiazol-2-yl)-5-diphenyl tetrazolium bromide assay. The total antioxidant potential was estimated by three different antioxidant model diphenylpicrylhydrazyl free radical scavenging activity, H
