Phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit: A comparative study
10.1016/S1995-7645(14)60241-8
- Author:
Dildar AHMED
1
;
Munim FATIMA
1
;
Sana SAEED
1
Author Information
1. Department of Chemistry, Forman Christian College (A Chartered University)
- Publication Type:Journal Article
- Keywords:
ABTS;
Antioxidant;
DPPH;
Epicarp;
FRAP;
Lagenaria siceraria;
Lipid peroxidation;
Mesocarp
- From:
Asian Pacific Journal of Tropical Medicine
2014;7(S1):S249-S255
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To conduct a comparative analysis of the phenolic and flavonoid contents and anti-oxidative potential of epicarp and mesocarp of Lagenaria siceraria fruit. Methods: The dried methanolic extracts of mesocarp and epicarp of the fruit and their hexane, chloroform, ethyl acetate, n-butanolic and aqueous fractions were subjected to antioxidant assays including ferric reducing antioxidant potential, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid, reducing power capacity, 2,2-diphenyl-1-picrylhydrazyl, lipid peroxidation inhibitory and phosphomolybdate assays. Total phenolic and flavonoid contents were also determined. Results: Ethyl acetate fractions of epicarp and mesocarp had considerable amounts of phenolics (243.50 and 109.50 μg/mL of gallic acid equivalents, respectively). 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity of ethyl acetate fractions of both the plant parts showed higher activity than vitamin C with IC
