HPTLC detection of altitudinal variation of the potential antivenin stigmasterol in different populations of the tropical ethnic antidote Rauvolfia serpentina
10.1016/S1995-7645(14)60287-X
- Author:
Abhijit DEY
1
;
Devendra Kumar PANDEY
2
Author Information
1. Department of Biological Sciences, Presidency University
2. Department of Biotechnology, School of Biotechnology and Biosciences, Lovely Professional University
- Publication Type:Journal Article
- Keywords:
Anti-venom;
Chromatogram;
Densitometry;
Secondary metabolites;
Snakebite
- From:
Asian Pacific Journal of Tropical Medicine
2014;7(S1):S540-S545
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine the altitudinal variation of stigmasterol, a potential antivenin, in roots from seven populations of Rauvolfia serpentina (L). Benth. ex Kurz. (Apocynaceae) (R. serpentina), an important herb found in Indian subcontinent which has long been used in the treatment of snakebite, blood pressure and schizophrenia. Methods: Altitudinal variation of stigmasterol content in R. serpentina roots was analyzed by high performance thin layer chromatography. Chromatography was performed on silica gel 60 F
