Screening of aphrodisiac property in sea slug, Aplysia dactylomela
10.1016/S1995-7645(14)60222-4
- Author:
Ridzwan HASHIM
1
;
Noor Atika Elliyana Mohd ROSLAN
1
;
Farah Hanis ZULKIPLI
1
;
Jamaluddin Mohd DAUD
2
Author Information
1. Department of Biomedical Science, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia
2. Department of Chemistry, Kulliyyah of Science, International Islamic University Malaysia
- Publication Type:Journal Article
- Keywords:
Aphrodisiac;
Aplysia dactylomela extract;
Mounting frequency;
Sildenafil citrate
- From:
Asian Pacific Journal of Tropical Medicine
2014;7(S1):S150-S154
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used; aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra® (5 mg/kg) being positive control while negative control received saline solution. Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference (P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract. Conlusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men.
