A comparative in vitro antioxidant potential profile of extracts from different parts of Fagonia cretica
10.1016/S1995-7645(14)60277-7
- Author:
Pervaiz IQBAL
1
;
Dildar AHMED
1
;
Muhammad Nadeem ASGHAR
1
Author Information
1. Department of Chemistry, Forman Christian College (A Chartered University)
- Publication Type:Journal Article
- Keywords:
ABTS;
Antioxidant potential;
Fagonia cretica;
TFC;
TPC
- From:
Asian Pacific Journal of Tropical Medicine
2014;7(S1):S473-S480
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate antioxidant and radical scavenging activities of organic extracts from fruit, roots and aerial parts of Fagonia cretica. Methods: Shed dried and powdered plant parts were initially extracted in methanol and subsequently partitioned in n-hexane, chloroform, ethyl acetate and 1-butanol successively. Antioxidant and radical scavenging potential of the methanol extracts and the fractions of each part were evaluated using total phenolic contents (TPC) and total flavonoid contents (TFC), 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation radicals scavenging, reducing power (potassium ferricyanide-trichloroacetic acid system), ferric ion reducing antioxidant potential, lipid peroxidation inhibition activity (linoleic acid system) and total antioxidant activity (phosphomolybdate) assays. Results: TPC and TFC values for methanol extracts and various fractions ranged from 0.23-4.30 mg/L gallic acid equivalents and from 30-545 mg/L rutin equivalents, respectively. Overall, methanol extracts and all the fractions of root and aerial parts showed higher TPC and TFC values. Methanol extracts and aqueous fractions of root and aerial parts and the n-butanol fraction of root showed lower EC
