Effect of preemptive local injection of ropivocaine with dexmedetomidine on mirror pain in rats and its mechanism

Author: Xi-Zhao HUANG ¹ ; Wei-Feng TU ¹ ; Jie PENG ¹ ; Rong-Fang DENG ¹ ; Kai MO ¹ ; Yi LU ¹ ; Xi-Zhao HUANG ² ; Zu-Rong HU ²
Author Information

1. Department of Anesthesiology, General Hospital of Guangzhou Military Command, Southern Medical University
2. Department of Anesthesiology, Guangdong Women and Children's Hospital
Publication Type:Journal Article
Keywords: Dexmedetomidine; Glial cells; Mirror-image pain; Ropivocaine; Transmission electron microscopy
From: Asian Pacific Journal of Tropical Medicine 2015;8(10):836-840
CountryChina
Language:Chinese
Abstract: Objective: To observe the effect of preemptive local injection of ropivocaine with dexmedetomidine on activation of glial cells and on the mirror pain in rats and its mechanism. Methods: A total of 48 adult male Sprague-Dawley rats (weighing 180 g-220 g) were included in the study and randomized into 3 groups, Group S, Group R, and Group RD