Correlation between microRNA-21 and expression of Th17 and Treg cells in microenvironment of rats with hepatocellular carcinoma
10.1016/j.apjtm.2015.07.021
- Author:
Shao-Xin YAO
1
;
Hong-Xia CAO
1
;
Guang SONG
1
;
Zang-Tuo LI
1
;
Wei-Tao ZHANG
1
;
Gui-Song ZHANG
2
Author Information
1. Department of Interventional Therapy, Affiliated Tangshan Workers Hospital of Hebei Medical University
2. Department of Interventional Therapy, Luanxian People's Hospital
- Publication Type:Journal Article
- Keywords:
Correlation analysis;
Hepatocellular carcinoma;
MiR-21;
Th17 cells;
Treg cells
- From:
Asian Pacific Journal of Tropical Medicine
2015;8(9):762-765
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the correlation between miR-21 and Treg/Th17 ratio in the microenvironment of rats with hepatocellular carcinoma. Methods: Diethylnitrosamine was used to build the hepatocellular carcinoma model of rats; the content of Treg cells and Th17 cells and the expression of miR-21 in the peripheral blood of rats with hepatocellular carcinoma were detected. The statistical analysis was performed on the correlation between miR-21 expression and Treg/Th17 ratio. Results: Hepatocellular carcinoma model of rats was successfully constructed. The proportion of Th17 cells among all CD4
