A Case of Primary Signet Ring Cell Carcinoma of Lung with Multiple Bone Metastasis.
10.4046/trd.2004.57.6.594
- Author:
Do Hyun SHIN
1
;
Hyoung Il KIM
;
Seon Kyo LIM
;
Seung Won LEE
;
Youn Mu JUNG
;
Young In CHOI
;
Seung Soo SHEEN
;
Joo Hun PARK
;
Yoon Jung OH
;
Kwang Joo PARK
;
Sung Chul HWANG
;
Rae Woong PARK
;
Chul SHIM
Author Information
1. Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea. sssheen@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Signet ring cell carcinoma;
Lung cancer
- MeSH:
Adenocarcinoma;
Carcinoma, Signet Ring Cell*;
Humans;
Liver;
Lower Extremity;
Lung Neoplasms;
Lung*;
Middle Aged;
Mucins;
Neoplasm Metastasis*;
Paralysis
- From:Tuberculosis and Respiratory Diseases
2004;57(6):594-598
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Signet ring cell carcinoma of lung is an unique variant of mucin producing adenocarcinoma which is characterized by abundant intracellular mucin accumulation. Only a few cases of primary signet ring cell carcinoma of lung have been reported in the world wide literature. And we have, recently experienced one case of primary signet ring cell carcinoma of lung. A 55 years old man was evaluated for paralysis of lower extremities and was found to have lung cancer in the left upper and lower lobe with pleural, multiple spinal, bone and liver metastases. Signet ring tumor cells were revealed by cytologic examination of pleural fluids. And there were no evidence of signet ring cell carcinoma of other organs. Primary signet ring cell carcinoma of lung seems to have an aggressive behavior and therapeutic modalities could be different from those for signet ring cell carcinomas from other organs. Therefore it is important to separate primary signet ring cell adenocarcinoma of lung from metastatic tumors.
