Larvicidal activity, inhibition effect on development, histopathological alteration and morphological aberration induced by seaweed extracts in Aedes aegypti (Diptera: Culicidae)
10.1016/j.apjtm.2015.11.011
- Author:
Ke-Xin YU
1
;
Ibrahim JANTAN
1
;
Ching-Lee WONG
2
;
Rohani AHMAD
3
Author Information
1. Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia
2. School of Biosciences, Taylor's University
3. Medical Entomology Unit, Infectious Disease Research Centre, Institute for Medical Research
- Publication Type:Journal Article
- Keywords:
Aedes aegypti;
Bryopsis pennata;
Dengue vector;
Mosquito larvicidal activity;
Padina australi;
Sargassum binderi
- From:
Asian Pacific Journal of Tropical Medicine
2015;8(12):1006-1012
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the larvicidal activity, inhibition effect on development, histopathological alteration and morphological aberration induced by the extracts derived from seaweeds Bryopsis pennata (B. pennata). Sargassum binderi (S. binderi) and Padina australis in Aedes aegypti (Ae. aegypti) larvae and to characterize the phytochemical components of the three seaweeds. Methods: Larvicidal activity of the seaweeds towards the larvae of Ae. aegypti was determined according to WHO. The inhibition effect of seaweeds was assessed by determining the mortality, adult emergence rate, larval and pupa duration of the treated larvae. Histopathological effect on midgut epithelium of larvae and morphological aberration induced by the methanol extracts were examined. Phytochemical analysis was done to determine the presence of alkaloids, saponins, steroids and terpenoids in the seaweeds. Results: Chloroform partition of B. pennata extract exhibited the strongest larvicidal activity (LC
