Immunological evidence of Zika virus transmission in Thailand
10.1016/j.apjtm.2016.01.017
- Author:
Nitwara WIKAN
1
;
Sutee YOKSAN
1
;
Duncan R. SMITH
1
;
Yupin SUPUTTAMONGKOL
2
;
Prasert AUEWARAKUL
2
Author Information
1. Institute of Molecular Biosciences, Mahidol University
2. Faculty of Medicine, Siriraj Hospital, Mahidol University
- Publication Type:Journal Article
- Keywords:
Emerging infectious diseases;
Serosurvey;
Thailand;
Zika virus
- From:
Asian Pacific Journal of Tropical Medicine
2016;9(2):141-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To identify immunological evidence of Zika virus transmission in Thailand. Methods: To undertake a preliminary serosurvey of possible exposure to Zika virus, 21 serum samples from cohort of acute undifferentiated fever patients were examined for immunoreactivity to Zika, Dengue, Japanese encephalitis and Chikungunya envelope antigens by Western blot analysis. Results: Twenty of the 21 serum samples showed immunoreactivity to at least one of the antigens, with seven samples showing immunoreactivity to all antigens. Of particular note, two serum samples showed immunoreactivity only to Zika envelope antigen, with no immunoreactivity to other envelope antigens. Conclusions: This study presents the first evidence of Zika virus transmission in Thailand, although as yet the relationship between transmission and possible cases of Zika fever in Thailand requires further investigation.
