First histopathological study in kidneys of rodents naturally infected with Leptospira pathogenic species from Yucatan, Mexico
10.1016/j.apjtm.2016.01.018
- Author:
Marco TORRES-CASTRO
1
;
Jorge ZAVALA-CASTRO
1
;
Fernando I. PUERTO
1
;
Leonardo GUILLERMO-CORDERO
2
;
Silvia HERNÁNDEZ-BETANCOURT
2
;
Edwin GUTIÉRREZ-RUÍZ
2
;
Piedad AGUDELO-FLÓREZ
3
;
Ronald PELÁEZ-SÁNCHEZ
3
Author Information
1. Centro de Investigaciones Regionales 'Dr. Hideyo Noguchi', Universidad Autónoma de Yucatán
2. Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán
3. Facultad de Medicina, Universidad CES
- Publication Type:Journal Article
- Keywords:
Leptospira spp;
Mus musculus;
Rattus rattus;
Renal histopathological lesions
- From:
Asian Pacific Journal of Tropical Medicine
2016;9(2):145-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To report the renal histological lesions in synanthropic rodents, Mus musculus and Rattus rattus, naturally infected with Leptospira spp., captured in a rural community in Yucatan, Mexico. Methods: Kidney samples of synanthropic rodents were collected from a rural community in Yucatan, Mexico. Polymerase chain reaction was used to detect Leptospira spp. infection. Tissue kidney was fixed in 10% buffered formalin, processed according to the usual techniques for paraffin inclusion, cut and stained with hematoxylin and eosin, and examined using a conventional electronic microscope. Results: A total of 187 rodents were captured. Nine individuals (4.8%) were positive for Leptospira spp. in the molecular analysis. All renal lesions observed in the histopathological study had been reported previously for Leptospira spp. infection. Conclusions: The histopathological lesions are present in the kidneys, plus the results of the polymerase chain reaction confirm that these rodents are true carriers of Leptospira spp.
