Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

Claudia Weilg; Fernando Mazulis; Wilmer Silva-caso; Carlos Alva-urcia; Juana Del Valle Mendoza; Olguita Del Aguila; Rosario Cerpa-polar; Wilmer Silva-caso; Juana Del Valle Mendoza; Erick Mattos-villena

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Seronegative disseminated Bartonella spp. infection in an immunocompromised patient

Author: Claudia WEILG ¹ ; Fernando MAZULIS ¹ ; Wilmer SILVA-CASO ¹ ; Carlos ALVA-URCIA ¹ ; Juana DEL VALLE MENDOZA ¹ ; Olguita DEL AGUILA ² ; Rosario CERPA-POLAR ² ; Wilmer SILVA-CASO ³ ; Juana DEL VALLE MENDOZA ³ ; Erick MATTOS-VILLENA ⁴
Author Information

1. Medicine School, Research Center and Innovation of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas
2. Pediatric Service, Hospital Nacional Edgardo Rebagliati Martins
3. Molecular Biology Laboratory, Instituto de Investigación Nutricional
4. Pediatric Hematology Service, Hospital Edgardo Rebagliati Martins
Publication Type:Journal Article
Keywords: B-cell acute lymphoblastic leukemia; Bartonella henselae; Bartonella spp.; Peru
From: Asian Pacific Journal of Tropical Medicine 2016;9(12):1222-1225
CountryChina
Language:Chinese
Abstract: An 11 year old, hispanic girl with a history of B-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with Bartonella henselae infection. The first molecularly diagnosed case of disseminated Bartonella henselae infection was reported in an immunocompromised patient in Lima, Peru. The analysis was confirmed by Polymerase Chain Reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient's past exposures with cats should also be elicited.