Survival rate and the determinants of progression from HIV to AIDS and from AIDS to the death in Iran: 1987 to 2016

Mohammad Mirzaei; Maryam Farhadian; Jalal Poorolajal; Parvin Afsar Kazerooni; Katayoun Tayeri; Younes Mohammadi

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Survival rate and the determinants of progression from HIV to AIDS and from AIDS to the death in Iran: 1987 to 2016

Author: Mohammad MIRZAEI ¹ ; Maryam FARHADIAN ² ; Jalal POOROLAJAL ³ ; Parvin Afsar KAZEROONI ⁴ ; Katayoun TAYERI ⁵ ; Younes MOHAMMADI ⁶
Author Information

1. Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences
2. Research Center for Health Sciences, Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences
3. Modeling of Noncommunicable Diseases Research Hamadan, Iran Center, Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences
4. HIV/AIDS Research Center, Shiraz University of Medical Sciences
5. Iranian Research Center of HIV and AIDS, Tehran University of Medical Sciences
6. Social Determinants of Health Research Center, School of Public Health, Hamadan University of Medical Sciences
Publication Type:Journal Article
Keywords: Cohort study; HIV/AIDS; Prognostic factor; Survival time; Tuberculosis
From: Asian Pacific Journal of Tropical Medicine 2019;12(2):72-78
CountryChina
Language:Chinese
Abstract: Objective: To examine the prognostic factors of progression from HIV to AIDS and AIDS to the death in people living with HIV/AIDS in Iran. Methods: In this registry-based retrospective cohort study, we recruited 28 873 HIV-infected people from 158 Behavioral Diseases Counseling Centers of Iran. Two outcomes of interest included survival rates from HIV diagnosis to AIDS and from AIDS to the death. We used Kaplan-Meier and Cox regression model to investigate survival rate and factors affecting on survival controlling effect of confounding factors. Results: The one, three, five, and ten-year survival rate from HIV to AIDS were 85%, 73%, 61% and 32%, and for AIDS to death were 90%, 81%, 74% and 55%, respectively. Multivariate Cox regression analysis indicated that the risk of progression from AIDS phase toward death in individuals with CD4 less than 200/mm