Pharmacological and analytical aspects of artemisinin for malaria: Advances and challenges

Author: Sravani KARRI ¹ ; Sanjay SHARMA ¹ ; Ginpreet KAUR ²
Author Information

1. NMIMS, School of Pharmacy and Technology Management
2. NMIMS, Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management
Publication Type:Journal Article
Keywords: Analytical techniques; Artemisinin; Malaria; Mechanism; Pharmacokinetics
From: Asian Pacific Journal of Tropical Medicine 2019;12(8):339-346
CountryChina
Language:Chinese
Abstract: Malaria remains a major tropical health burden owing to the development of resistance and decreased sensitivity to the frequently used conventional antimalarial drugs. The drug like artemisinin possesses potent antimalarial activities, but has some limitations. Therefore, new strategies are to be implemented for optimal utilization of artemisinin to improve its therapeutic effectiveness and to overcome its limitations. The present review focuses on present scenario of malaria and pharmacological as well as analytical aspects of artemisinin. Data from 2000 to 2018 were collected from NCBI for understanding the various analytical techniques used for estimation of artemisinin. This review will reveal the facts about artemisinin which can be utilized to develop novel drug delivery system either in a combination or as alone for the wellbeing of the patients suffering from malaria.