The phytochemical and pharmacological properties of artocarpin from Artocarpus heterophyllus

Author: Nik Nurul DAUD ¹ ; Nordin SIMBAK ¹ ; Abdi SEPTAMA ² ; Eldiza RAHMI ³
Author Information

1. Faculty of Medicine, Universiti Sultan Zainal Abidin
2. Research Center for Chemistry, Indonesian Institute of Sciences, Kawasan PUSPIPTEK Serpong
3. Faculty of Medicine, UPN Veteran Jl. Rs. Fatmawati
Publication Type:Journal Article
Keywords: Artocarpin; Artocarpus sp.; Flavonoid; Pharmacological; Phytochemical
From: Asian Pacific Journal of Tropical Medicine 2020;13(1):1-7
CountryChina
Language:Chinese
Abstract: Artocarpus heterophyllus Lam. (Moraceae) has been traditionally used in treating various diseases such as diabetes, diarrhea, malarial fever, inflammation, wound healing and other diseases. Since various bioactive compounds have been found in this plant, this review focuses on the phytochemical and pharmacological properties of a potent bioactive compound artocarpin. Despite its various functions, a mechanistic review on this compound has not been reviewed specifically. Here, pharmacological studies in vitro and in vivo on artocarpin are discussed thoroughly stressing on anticancer, antimicrobial, anti-tyrosinase, antioxidant and antiinflammatory aspects of artocarpin. This review would be beneficial for future study to show the competency of natural products for theirtherapeutic characteristics.