Short-term Effects of Ambient Air Pollution on Emergency Department Visits for Asthma: An Assessment of Effect Modification by Prior Allergic Disease History.
- Author:
Juhwan NOH
1
;
Jungwoo SOHN
;
Jaelim CHO
;
Seong Kyung CHO
;
Yoon Jung CHOI
;
Changsoo KIM
;
Dong Chun SHIN
Author Information
- Publication Type:Original Article
- Keywords: Air pollution; Asthma; Emergencies; Time series analysis; Effect modifier; Korea
- MeSH: Air Pollutants; Air Pollution*; Asthma*; Dermatitis, Atopic; Emergencies*; Emergency Service, Hospital*; Humans; Insurance, Health; Korea; Nitrogen Dioxide; Ozone; Particulate Matter; Rhinitis, Allergic; Seasons; Seoul; Sulfur Dioxide
- From:Journal of Preventive Medicine and Public Health 2016;49(5):329-341
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVES: The goal of this study was to investigate the short-term effect of ambient air pollution on emergency department (ED) visits in Seoul for asthma according to patients’ prior history of allergic diseases. METHODS: Data on ED visits from 2005 to 2009 were obtained from the Health Insurance Review and Assessment Service. To evaluate the risk of ED visits for asthma related to ambient air pollutants (carbon monoxide [CO], nitrogen dioxide [NO₂], ozone [O₃], sulfur dioxide [SO₂], and particulate matter with an aerodynamic diameter <10 μm [PM₁₀]), a generalized additive model with a Poisson distribution was used; a single-lag model and a cumulative-effect model (average concentration over the previous 1-7 days) were also explored. The percent increase and 95% confidence interval (CI) were calculated for each interquartile range (IQR) increment in the concentration of each air pollutant. Subgroup analyses were done by age, gender, the presence of allergic disease, and season. RESULTS: A total of 33 751 asthma attack cases were observed during the study period. The strongest association was a 9.6% increase (95% CI, 6.9% to 12.3%) in the risk of ED visits for asthma per IQR increase in O₃ concentration. IQR changes in NO₂ and PM₁₀ concentrations were also significantly associated with ED visits in the cumulative lag 7 model. Among patients with a prior history of allergic rhinitis or atopic dermatitis, the risk of ED visits for asthma per IQR increase in PM₁₀ concentration was higher (3.9%; 95% CI, 1.2% to 6.7%) than in patients with no such history. CONCLUSIONS: Ambient air pollutants were positively associated with ED visits for asthma, especially among subjects with a prior history of allergic rhinitis or atopic dermatitis.
