Oxfendazole as successful treatment of Taenia hydatigena metacestodes in naturally infected pigs
10.1016/j.apjtb.2015.03.013
- Author:
Luis Antonio GOMEZ-PUERTA
1
;
Armando Emiliano GONZALEZ
1
;
Cesar GAVIDIA
1
;
Maria Teresa LOPEZ-URBINA
1
;
Viterbo AYVAR
2
;
Hector Hugo GARCIA
2
;
Hector Hugo GARCIA
3
Author Information
1. School of Veterinary Medicine, National University of San Marcos
2. Cysticercosis Elimination Program and Center for Global Health Tumbes, Cayetano Heredia University
3. Department of Microbiology, School of Sciences, Cayetano Heredia University
- Publication Type:Journal Article
- Keywords:
Cysticercus tenuicollis;
Oxfendazole;
Taenia hydatigena;
Treatment
- From:Asian Pacific Journal of Tropical Biomedicine
2015;5(11):971-973
- CountryChina
- Language:Chinese
-
Abstract:
The efficacy of oxfendazole (OFZ) on Taenia hydatigena metacestodes, also called Cysticercus tenuicollis ( C. tenuicollis), was studied in 648 raising pigs. This study was performed in Tumbes Department in Peru, an endemic area for cysticercosis. Pigs were randomized in two groups; untreated group (. n = 142) did not receive any treatment and treated group ( n = 506) received OFZ treatment at a single dose of 30 mg/kg body weight. Six months after treatment, the pigs were necropsied. The prevalence of infection by C. tenuicollis among the pigs was 27.5% (39/142) and 2.0% (10/506) in untreated and treated groups, respectively. Untreated group was infested only with viable cysts, whereas treated group had no viable cysts. All the cysts found in treated group presented degeneration, with a thick membrane, and they contained milky fluid and fibrous tissue. A single dose of OFZ was effective against C. tenuicollis, thus providing an alternative drug for controlling this parasite in pigs.
