Wound healing potential of Althaea officinalis flower mucilage in rabbit full thickness wounds
10.1016/j.apjtb.2015.07.018
- Author:
Robab VALIZADEH
1
;
Ali Asghar HEMMATI
1
;
Gholamreza HOUSHMAND
1
;
Sara BAYAT
1
;
Mohammad BAHADORAM
1
;
Sara BAYAT
2
;
Mohammad BAHADORAM
2
Author Information
1. Department of Pharmacology and Toxicology, Herbal Research Center, Pharmacy School, Ahvaz Jundishapur University of Medical Sciences
2. Medical Student Research Committee, Ahvaz Jundishapur University of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Althaea flower;
Antibacterial;
Mucilage;
Rabbit;
Skin;
Wound
- From:Asian Pacific Journal of Tropical Biomedicine
2015;5(11):937-943
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate and practically demonstrate the influence of Althaea officinalis flower mucilage as a plant known in Iran's and other Middle Eastern countries' traditional medicine for its wound healing properties. Methods: Animals were divided into 6 groups of 5 cases including a non-treated group as the negative control group receiving no treatment, a group treated with eucerin as the positive control group, a phenytoin 1% group as a standard group treated topically with phenytoin 1% hand-made ointment, and treatment groups treated with hand-made Althaea officinalis flower mucilage (AFM) ointment in a eucerin base with different concentrations (5%, 10%, 15%). Results: Among the treatment groups, the AFM 15% ointment showed the best result. Wound healing duration was reduced by the surface application of these groups. Wound closure was completed on Days 14 and 15 in the AFM 15% ointment and phenytoin 1% groups, respectively. No significant difference was observed in healing period between these groups. Conclusions: In conclusion, AFM 15% ointment was found to reduce wound healing time without any significant difference with the phenytoin 1% ointment. The authors suggest increased AFM effectiveness in when combined with phenytoin or other effectual plants.
