Preventive management of uric acid nephrolithiasis with potassium citrate.
- Author:
Byung Woo] SON
1
;
Yeo Deuk YOON
;
Sung Kwang CHUNG
;
Yoon Kyu PARK
;
Dong Kyu CHO
Author Information
1. Department of Urology, Kyungpook University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
uric acid;
preventive management
- MeSH:
Animals;
Calcium;
Humans;
Hydrogen-Ion Concentration;
Nephrolithiasis*;
Potassium Citrate*;
Potassium*;
Sutures;
Uric Acid*
- From:Korean Journal of Urology
1991;32(6):937-940
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Eleven patients with uric acid nephrolithiasis(Five with uric acid stones alone and six with both uric acid and calcium stone) underwent long-term treatment(0.5 to 3.75 years, mean of 2.33 years) with potassium citrate(30 to 80 mEq/day. usually 60mEq/day). Urinary pH increased from low(5.0-6.0) to normal(6.5-7.0) during treatment. Urinary content of uric acid which was 584+/-150 mg, day. slightly increased to 595+/-163 mg/day following treatment. Serum content of uric acid which was 6.45+/-0.9 mg%, slightly decreased to 6.1+/-0.8 mg%. The protein matrix was round in all 11 cases. And 4 types of nucleus were found. which were ca. oxalate, ca. phosphate, dried blood and suture material During the period' (Jan. 1987-Mar. 1990) of preventive management(enough fluid intake. restiction of animal protein and Polycitra-K), no new stones were found.
