Medicinal plants with hepatoprotective activity in Iranian folk medicine
10.1016/S2221-1691(15)30159-3
- Author:
Majid ASADI-SAMANI
1
;
Mahmoud RAFIEIAN-KOPAEI
1
;
Najme KAFASH-FARKHAD
2
;
Ebrahim ALINIA-AHANDANI
2
;
Nafiseh AZIMI
3
;
Ali FASIHI
4
Author Information
1. Medical Plants Research Center, Shahrekord University of Medical Sciences
2. Department of Biology, Faculty of Science, Urmia University
3. Department of Biology, Science and Research Branch, Islamic Azad University
4. Department of Genetics, Faculty of Biology Science, Tarbit Modares University
- Publication Type:Journal Article
- Keywords:
CC14;
Compounds;
Iran;
Liver;
Medicinal plants;
Therapeutic uses
- From:Asian Pacific Journal of Tropical Biomedicine
2015;5(2):146-157
- CountryChina
- Language:Chinese
-
Abstract:
There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for liver. In this review, we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine, with focus on their hepatoprotective effects particularly against CC14 agent. In this study, online databases including Web of Science, PubMed, Scopus, and Science Direct were searched for papers published from January 1970 to December 2013. Search terms consisted of medicinal plants, traditional medicine, folk medicine, hepatoprotective, Iran, liver, therapeutic uses, compounds, antioxidant, CC14, anti-inflammatory, and antihepatotoxic, hepatitis, alone or in combination. Allium hirtifolium Boiss., Apium graveolens L., Cynara scolymus, Berberis vulgaris L., Calendula officinalis, Nigella sativa L., Taraxacum officinale, Tragopogon porrifolius, Prangos ferulacea L., Allium sativum, Marrubium vulgare, Ammi majus L., Citrullus lanatus Thunb, Agrimonia eupatoria L. and Prunus armeniaca L. are some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk medicine. Out of several leads obtained from plants containing potential hepatoprotective agents, silymarin, β-sitosterol, betalain, neoandrographolide, phyllanthin, andrographolide, curcumin, picroside, hypophyllanthin, kutkoside, and glycyrrhizin have been demonstrated to have potent hepatoprotective properties. Despite encouraging data on possibility of new discoveries in the near future, the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.
