Antiplasmodial activity of traditional polyherbal remedy from Odisha, India: Their potential for prophylactic use

Author: Prakash Bangalore NAGENDRAPPA ¹ ; Padma VENKATASUBRAMANIAN ¹ ; Prakash Bangalore NAGENDRAPPA ² ; Prakash Bangalore NAGENDRAPPA ³ ; Jean-François FRANETICH ³ ; Audrey LORTHIOIS ³ ; Dominique MAZIER ³ ; Frederick GAY ⁴ ; Dominique MAZIER ⁴
Author Information

1. Institute of Trans-Disciplinary Health Sciences and Technology, Foundation for Revitalisation of Local Health Traditions
2. Manipal University
3. Cimi-Paris (UPMC UMRS CR7, Inserm U1135, CNRS ERL 8255)
4. AP-HP, Pitié-Salpêtrière Hospital Group, Parasitology-Mycology Department
Publication Type:Journal Article
Keywords: Antiplasmodial activity; Malaria prophylaxis; Plasmodium; Polyherbal remedy
From:Asian Pacific Journal of Tropical Biomedicine 2015;5(12):982-986
CountryChina
Language:Chinese
Abstract: Objective: To evaluate the potential prophylactic activity of traditional polyherbal remedy against malaria. Methods: A traditional polyherbal remedy against malaria from Odisha, India was evaluated for its potential prophylactic activity using in vitro hepatic cell lines assay and the murine malaria system Plasmodium yoelii yoelii/Anopheles stephensi. Results: The polyherbal extract inhibited the Plasmodium yoelii hepatic stages in vitro (IC