A case of Myasthenia Gravis associated with Premature ovarian failure and thyroid autoanibodies.
- Author:
Dong Suk HAM
1
;
Sei Hee CHANG
;
Young Chul YOUN
;
Woo Jung KIM
;
Oh Sang KWON
;
Hyoung Moo PARK
;
Doo Eung KIM
;
Kwang Woo LEE
Author Information
1. Department of Neurology, College of Medicine, Chungang University, Korea.
- Publication Type:Case Report
- Keywords:
Myasthenia Gravis;
Premature Ovarian Failure;
Thyroid Autoimmunity
- MeSH:
Acetylcholine;
Antibodies;
Arthritis, Rheumatoid;
Autoantibodies;
Autoantigens;
Autoimmune Diseases;
Humans;
Lupus Erythematosus, Systemic;
Muscle, Skeletal;
Myasthenia Gravis*;
Primary Ovarian Insufficiency*;
Thyroid Diseases;
Thyroid Gland*
- From:Journal of the Korean Neurological Association
1995;13(2):362-366
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Myasthenia gravis (MG) is regarded as autoimmune disorder of neuromuscular transmission and apparently is due to formation of humoral antibody that cross-link to acetylcholine receptor at skeletal muscle end plate. Patients with autoimmune diseases often have circulating antibodies to a variety of different autoantigens and show a variety of manifestations of autoimmune diseases in more than one organ. Therefore, MG patients frequently have manifestations of autoimmune diseases such as thyroid disease, rheumatoid arthritis and systemic lupus erythematosus. But MG in association with premature ovarian failure (POF) rarely has been described. A case of MG with POF and thyroid autoantibodies was experienced and presented with a brief review of literature.
