Chemical composition of Rosmarinus officinalis essential oil and antioxidant action against gastric damage induced by absolute ethanol in the rat
10.1016/j.apjtb.2015.09.027
- Author:
Christiane TAKAYAMA
1
;
Ana Cristina Alves DE ALMEIDA
1
;
Alba Regina Monteiro SOUZA-BRITO
1
;
Felipe Meira DE-FARIA
2
;
Ricardo José DUNDER
2
;
Luis Paulo MANZO
2
;
Eduardo Augusto Rabelo SOCCA
2
;
Alba Regina Monteiro SOUZA-BRITO
2
;
Leonia Maria BATISTA
3
;
Marcos José SALVADOR
4
;
Anderson LUIZ-FERREIRA
5
Author Information
1. Functional and Structural Biology Department, Biology Institute, Campinas State University
2. Pharmacology Department, Faculty of Medical Sciences, Campinas State University
3. Department of Pharmaceutical Sciences, Federal University of Paraiba
4. Plant Physiology Department, Biology Institute, Campinas State University
5. Federal University of Goiás, Institute of Biotechnology, Nucleus of Biological Sciences, Regional Catalão
- Publication Type:Journal Article
- Keywords:
Antioxidant activity;
Antioxidant enzymes;
Gastric ulcer;
Rosmarinus officinalis L.
- From:Asian Pacific Journal of Tropical Biomedicine
2016;6(8):677-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the antioxidant activity of the essential oil obtained from Rosmarinus officinalis (R. officinalis) in ethanol-induced gastric ulcer model in vivo. Methods The antioxidant properties of the essential oil obtained from R. officinalis were evaluated against gastric injury induced by absolute ethanol. Gastric tissues were prepared to enzymatic assays. The levels of glutathione, lipid peroxides, and the activities of glutathione peroxidase, superoxide dismutase and myeloperoxidase were measured. Results Ethanol produced severe hemorrhagic lesions in the stomach with ulcerative lesion of (140.2 ± 37.2) mm
