Phytochemical screening and evaluation of cytotoxic and hypoglycemic properties of Mangifera indica peels
- Author:
Sabiha CHOWDHURY
1
;
Saikat Kumar PODDAR
1
;
Sanjana HAQUE
1
;
Abhijit SUKUL
1
;
Md. Mahabob Ullah MAZUMDER
1
;
Sarah ZAHEEN
2
;
Farah Ashrafi NOOR
2
;
Najneen AHMED
2
;
Sauda Binte SUNJIDA
2
;
Nusrat AKBAR
2
Author Information
- Publication Type:Journal Article
- Keywords: Cytotoxicity; Hypoglycemia; Mangifera indica; Phytoconstituents
- From:Asian Pacific Journal of Tropical Biomedicine 2017;7(1):49-52
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the presence of different phytoconstituents in Mangifera indica (M. indica) peel and evaluate its cytotoxicity to Artemia salina and hypoglycemic potential in Swiss albino mice. Methods The methanolic extract of M. indica peel was used to determine the presence of phytoconstituents. Brine shrimp lethality bioassay method was followed to determine the cytotoxic potential of plant extract. In the case of hypoglycemic activity, oral administration of extract at 200 and 400 mg/kg and standard glibenclamide at 10 mg/kg was done, followed by determining the percentage of reduction of plasma glucose from the initial level. Results The methanolic extract of M. indica peel showed the presence of flavonoid, saponin, steroid, tannins, terpenoids, glycosides and alkaloids. In brine shrimp lethality bioassay, the LC
