Elaborate evaluation of serum and tissue oxidized LDL level with darapladib therapy: A feasible diagnostic marker for early atherogenesis
10.1016/j.apjtb.2016.11.014
- Author:
Teuku HERIANSYAH
1
;
Aditya Angela ADAM
2
;
Titin Andri WIHASTUTI
2
;
Mohammad SAIFUR ROHMAN
3
Author Information
1. Department of Cardiology, Faculty of Medicine, Syiah Kuala University
2. Department of Biomedicine, Faculty of Medicine, Brawijaya University
3. Department of Cardiology, Saiful Anwar Hospital
- Publication Type:Journal Article
- Keywords:
Aorta;
Darapladib;
Foam cell;
Lp-PLA;
OxLDL;
Serum
- From:Asian Pacific Journal of Tropical Biomedicine
2017;7(2):134-138
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare oxidized low density lipoprotein (oxLDL) levels in serum and vascular wall of Sprague-Dawley rats, identify their patterns in 8 weeks and 16 weeks of dyslipidemia induced by high fat diet, compare foam cells in aorta of each group and investigate lipoprotein-associated phospholipase A