New Insights in the Clinical Understanding of Behcet's Disease.
- Author:
Sung Bin CHO
1
;
Suhyun CHO
;
Dongsik BANG
Author Information
- Publication Type:Review ; Research Support, Non-U.S. Gov't
- Keywords: Behcet's disease; epidemiology; etiopathogenesis; animal model; diagnosis; new biologics
- MeSH: Animals; *Behcet Syndrome/epidemiology/immunology/therapy; Biological Therapy/*trends; Disease Models, Animal; Humans; Prevalence; *World Health
- From:Yonsei Medical Journal 2012;53(1):35-42
- CountryRepublic of Korea
- Language:English
- Abstract: Behcet's disease is a chronic relapsing multisystemic inflammatory disorder characterized by four major symptoms (oral aphthous ulcers, genital ulcers, skin lesions, and ocular lesions) and occasionally by five minor symptoms (arthritis, gastrointestinal ulcers, epididymitis, vascular lesions, and central nervous system symptoms). Although the etiology of Behcet's disease is still unknown, there have been recent advances in immunopathogenic studies, genome-wide association studies, animal models, diagnostic markers, and new biological agents. These advances have improved the clinical understanding of Behcet's disease and have enabled us to develop new treatment strategies for this intractable disease, which remains one of the leading causes of blindness.
