Probiotics with anti-type 2 diabetes mellitus properties: targets of polysaccharides from traditional Chinese medicine.
10.1016/S1875-5364(22)60210-3
- Author:
Lun WU
1
;
Yue GAO
2
;
Yang SU
3
,
4
;
Jing LI
2
;
Wen-Chen REN
2
;
Qiu-Hong WANG
5
;
Hai-Xue KUANG
6
Author Information
1. Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
2. School of Pharmacy, Heilongjiang University of Chinese Medicine, Key Laboratory of Medicinal Materials, Chinese Academy of Sciences, Harbin 150040, China.
3. School of Pharmacy, Heilongjiang University of Chinese Medicine, Key Laboratory of Medicinal Materials, Chinese Academy of Sciences, Harbin 150040, China
4. Faculty of Microbiology and Immunogenetics, University of California, Los Angeles, CA 90095, USA. Electronic address: 2601126924@qq.com.
5. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510000, China.
6. School of Pharmacy, Heilongjiang University of Chinese Medicine, Key Laboratory of Medicinal Materials, Chinese Academy of Sciences, Harbin 150040, China. Electronic address: 13163670957@163.com.
- Publication Type:Review
- Keywords:
Intestinal microflora;
Prebiotics;
Traditional Chinese medicine polysaccharide;
Type 2 diabetes mellitus
- MeSH:
Blood Glucose/metabolism*;
Diabetes Mellitus, Type 2/metabolism*;
Humans;
Lipids;
Medicine, Chinese Traditional;
Polysaccharides/pharmacology*;
Probiotics/therapeutic use*
- From:
Chinese Journal of Natural Medicines (English Ed.)
2022;20(9):641-655
- CountryChina
- Language:English
-
Abstract:
Traditional Chinese medicine polysaccharides is a biologically active ingredient that is not easy to be digested. It is fermented by intestinal microflora to promote qualitative and selective changes in the composition of the intestinal microbiome, which often result in beneficial effects on the health of the host. People call it "prebiotics". In this review, we systematically summarized the anti-diabetic effect of traditional Chinese medicine polysaccharides. These polysaccharides regulate the metabolism of sugar and lipids by inter-influence with the intestinal microflora, and maintain human health, while improving type 2 diabetes-like symptoms such as high blood glucose, and abnormal glucose and lipid metabolism.
