Unusual global outbreak of monkeypox: what should we do?
10.1007/s11684-022-0952-z
- Author:
Miaojin ZHU
1
;
Jia JI
1
;
Danrong SHI
1
;
Xiangyun LU
1
;
Baohong WANG
1
;
Nanping WU
1
;
Jie WU
2
;
Hangping YAO
3
;
Lanjuan LI
4
Author Information
1. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China.
2. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China. zjwujie@zju.edu.cn.
3. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China. yaohangping@zju.edu.cn.
4. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, China. ljli@zju.edu.cn.
- Publication Type:Review
- Keywords:
infectious diseases;
monkeypox;
poxviruses;
vaccine
- MeSH:
COVID-19;
Disease Outbreaks/prevention & control*;
Humans;
Monkeypox/epidemiology*;
Monkeypox virus;
Pandemics/prevention & control*
- From:Frontiers of Medicine
2022;16(4):507-517
- CountryChina
- Language:English
-
Abstract:
Recently, monkeypox has become a global concern amid the ongoing COVID-19 pandemic. Monkeypox is an acute rash zoonosis caused by the monkeypox virus, which was previously concentrated in Africa. The re-emergence of this pathogen seems unusual on account of outbreaks in multiple nonendemic countries and the incline to spread from person to person. We need to revisit this virus to prevent the epidemic from getting worse. In this review, we comprehensively summarize studies on monkeypox, including its epidemiology, biological characteristics, pathogenesis, and clinical characteristics, as well as therapeutics and vaccines, highlighting its unusual outbreak attributed to the transformation of transmission. We also analyze the present situation and put forward countermeasures from both clinical and scientific research to address it.
