Extubation Time by Birth Weight and the Predictors for Success/Failure at the First Extubation in Extremely Low Birth Weight Infants.
- Author:
Chang Won CHOI
1
;
Sung Eun PARK
;
Ga Won JEON
;
Eun Jung YOO
;
Jong Hee HWANG
;
Yun Sil CHANG
;
Won Soon PARK
Author Information
1. Department of Pediatrics, Samsung Medical Center, College of Medicine, Sungkyunkwan University, Seoul, Korea. wspark@smc.samsung.co.kr
- Publication Type:Original Article
- Keywords:
Extubation;
Predictor;
Extremely low birth weight infant
- MeSH:
Birth Weight*;
Body Weight;
Humans;
Incidence;
Infant*;
Infant, Extremely Low Birth Weight;
Infant, Low Birth Weight*;
Infant, Newborn;
Membranes;
Mortality;
Nutritional Status;
Parturition*;
Rupture;
Seoul;
Sepsis;
Ventilators, Mechanical
- From:Korean Journal of Pediatrics
2005;48(5):488-494
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To outline the aspects of extubation by birth weight and find the predictors for success/ failure at the first extubation in extremely low birth weight infants. METHODS: One hundred thirteen extremely low birth weight infants(< 1,000 g) who were admitted to NICU at Samsung Seoul Hospital between Jan. 2000 and Jun. 2004 were enrolled. Clinical characteristics that are thought to be related with extubation success or failure were compared with the success and the failure of the first extubation. RESULTS: As the birth weight decreased, extubation success day was significantly delayed:16+/-3 day(d) in 900-999 g; 20+/-3 d in 800-899 g; 35+/-4 d in 700-799 g; 37+/-9 d in 600-699 g; 49+/-12 d in < or =599 g. 25 out of 113 infants(22%) failed the first extubation. Preterm premature rupture of membrane was associated with extubation success, and air leak was associated with extubation failure, with a borderline significance. Postnatal and corrected age and body weight at the first extubation, nutritional status, and ventilator settings were not associated with extubation success or failure. Extubation success day was significantly delayed, and the incidence of late-onset sepsis and mortality was significant higher in the failure of the first extubation. CONCLUSION: We could not find significant predictors for success/failure at the first extubation. The failure of the first extubation had an increased risk of late-onset sepsis and death. Further studies are needed to find the predictors for extubation success/failure.
