A Case of Secondary Amyloidosis Presenting as Massive Gastrointestinal Bleeding.
- Author:
Hee KIM
1
;
Sam Ryong JEE
;
Sang Bong LEE
;
Jae Ho LEE
;
Sung Jae PARK
;
Eun Taek PARK
;
Yeon Jae LEE
;
Sang Hyuk LEE
;
Sang Young SEOL
;
Jung Myung CHUNG
Author Information
1. Department of Internal Medicine, Inje University College of Medicine, Paik Hospital, Busan, Korea. tokimom@nate.com
- Publication Type:Case Report ; English Abstract
- Keywords:
Amyloidosis;
Massive hematochezia
- MeSH:
Aged;
Amyloidosis/*complications/diagnosis;
Female;
Gastrointestinal Hemorrhage/*etiology;
Humans;
Intestinal Diseases/*complications/diagnosis
- From:The Korean Journal of Gastroenterology
2006;47(5):397-401
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amyloidosis is a disorder characterized by extracellular deposition of amyloid in various tissues and organs. Gastrointestinal manifestations including gastroparesis, constipation, malabsorption, intestinal pseudo-obstruction, and bleeding are common. GI bleeding is a rare initial symptom which can be fatal in some cases. Absence of systemic symptoms and nonspecific endoscopic findings in amyloidosis may make diagnosis difficult. Therefore, amyloidosis-induced GI bleeding should be considered in patients with an obscure hemorrhage. Recently, we experienced a 65-year-old woman who presented with massive hematochezia as a manifestations of amyloidosis. Colonoscopy and SMA angiography showed massive bleeding in the small and large intestine. Colonoscopic biopsy established amyloidosis. We report this case with a review of the relevant literatures.
