A Sero-epidemiological Study on Transfusion-Transmissible Infectious among Volunteer Blood Donors From 2016 to 2020 in Nanjing.
10.19746/j.cnki.issn.1009-2137.2022.05.042
- Author:
Tao FENG
1
;
Rui ZHU
1
;
Chun ZHOU
1
;
Xiang-Ping CHEN
2
;
Ni-Zhen JIANG
1
;
Shao-Wen ZHU
3
Author Information
1. Jiangsu Blood Center, Jiangsu Cancer Hospital, Nanjing 210042, Jiangsu Province, China.
2. Department of Gastroenterology and Oncology, Jiangsu Cancer Hospital, Nanjing 210042, Jiangsu Province, China.
3. Jiangsu Blood Center, Jiangsu Cancer Hospital, Nanjing 210042, Jiangsu Province, China. E-mail: zhushaowen@jsblood.com.cn.
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
hepatitis C virus;
human immunodeficiency virus;
treponema pallidum;
volunteer blood donor
- MeSH:
Blood Donors;
HIV Infections/epidemiology*;
Hepatitis B Surface Antigens;
Humans;
Prevalence;
Seroepidemiologic Studies;
Syphilis;
Volunteers
- From:
Journal of Experimental Hematology
2022;30(5):1572-1576
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the status of transfusion-transmissible infection (TTI) among voluntary blood donors in Nanjing in recent five years, in order to provide data support for the recruitment of blood donors and formulation and updating of blood screening strategies.
METHODS:HIV/HBV/HCV/TP serological markers were detected by ELISA in 487 120 blood donors in Nanjing from 2016 to 2020. Confirmatory assay was applied in anti-HIV positive samples by Nanjing Municipal Center for Disease Control and Prevention. The prevalence of TTI was calculated and the trend of disease was analyzed under different demographic groups.
RESULTS:The total positive rate of TTI in blood donors was 0.49% (2 411/487 120), in which the overall seroprevalence rate of HBsAg, anti-HCV, anti-HIV and anti-TP was 0.23%, 0.09%, 0.01% and 0.16%, respectively. The overall prevalence of HIV and TP remained relatively steady (P>0.05), whereas HBV and HCV decreased year by year (P<0.05). The prevalence of TTI was higher among people with lower education level, high age group and first-time blood donation.
CONCLUSION:The prevalence of TTI among voluntary blood donors in Nanjing is at a low level from 2016 to 2020, but the risk still exists. The recruitment of regular donors and the improvement of blood screening technology can effectively reduce the risk of TTI.
