Clinical Role of M Protein in Multiple Myeloma and Lymphoma --Review.
10.19746/j.cnki.issn.1009-2137.2022.04.050
- Author:
Liu-Yun ZHANG
1
;
Yun-Hui XIANG
1
;
Yan-Ying LI
1
;
Juan ZHANG
2
Author Information
1. School of Medicine University of Electronic Science and Technology of China, Chengdu 610054, Sichuan Province, China.
2. Department of Clinical Medical Laboratory Center, The Affiliated Hospital of University of Electronic Science and Technology of China & Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China. E-mail: zhangjuan82@126.com.
- Publication Type:Review
- Keywords:
lymphoma;
M protein;
genetic abnormality;
multiple myeloma
- MeSH:
Humans;
Lymphoma;
Multiple Myeloma/pathology*;
Prognosis;
Waldenstrom Macroglobulinemia/pathology*
- From:
Journal of Experimental Hematology
2022;30(4):1281-1285
- CountryChina
- Language:Chinese
-
Abstract:
M protein is often expressed in multiple myeloma and also can be detected in several lymphoma such as Waldenstrm macroglobulinaemia. M protein level can reflect the malignant degree and even genetic abnormality of multiple myeloma and lymphoma to some extent to predict the progress of the diseases, and the therapeutic response and prognosis of the disease can be evaluated by monitoring the M protein level and its change degree. This article reviews the role of M protein in the progression and prognosis of multiple myeloma and lymphoma, and discusses the differences in M protein expression between multiple myeloma and lymphoma, in order to provide new insights for clinical diagnosis, monitoring and evaluation of therapeutic effect.
