Health economic considerations of genetic disease screening - take Down syndrome as an example.
10.3760/cma.j.cn511374-20220424-00275
- Author:
Nan WANG
1
;
Lijian ZHAO
;
Shunyao WANG
;
Yu YAO
;
Jesse LI-LING
Author Information
1. Institute of Public Health and Social Security, School of Public Administration, Hunan University, Changsha, Hunan 410082, China. njyaoyu@163.com.
- Publication Type:Journal Article
- MeSH:
Cost-Benefit Analysis;
Down Syndrome/genetics*;
Genetic Testing;
Humans
- From:
Chinese Journal of Medical Genetics
2022;39(10):1053-1057
- CountryChina
- Language:Chinese
-
Abstract:
The ongoing development of high-throughput sequencing technology and continuous decline of sequencing cost have made it possible to carry out large-scale screening for genetic diseases, which are the main component of birth defects. The screening of genetic diseases is expected to significantly reduce the rate of birth defects and the burden of genetic diseases to the affected families and the society. Taking Down syndrome as an example, through the analysis of the cost-benefit ratio of relevant screening programs, this article has summarized the socio-economic indicators to be considered during the design and development of genetic disease screening.
