Research on the effect of multi-modal transcranial direct current stimulation on stroke based on electroencephalogram.
10.7507/1001-5515.202206018
- Author:
Hongli YU
1
;
Shaoqian ZHANG
1
;
Chunfang WANG
2
;
Lei GUO
1
;
Guizhi XU
1
Author Information
1. State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin 300130, P. R. China.
2. Rehabilitation Medical Department, Tianjin Union Medical Center, Tianjin 300121, P. R. China.
- Publication Type:Journal Article
- Keywords:
Electroencephalogram;
Multi-scale intrinsic fuzzy entropy;
Stroke;
Transcranial direct current stimulation
- MeSH:
Humans;
Transcranial Direct Current Stimulation/methods*;
Electroencephalography;
Stroke Rehabilitation;
Stroke/therapy*;
Electrodes
- From:
Journal of Biomedical Engineering
2022;39(5):966-973
- CountryChina
- Language:Chinese
-
Abstract:
As an emerging non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS) has received increasing attention in the field of stroke disease rehabilitation. However, its efficacy needs to be further studied. The tDCS has three stimulation modes: bipolar-stimulation mode, anode-stimulation mode and cathode-stimulation mode. Nineteen stroke patients were included in this research (10 with left-hemisphere lesion and 9 with right). Resting electroencephalogram (EEG) signals were collected from subjects before and after bipolar-stimulation, anodal-stimulation, cathodal-stimulation, and pseudo-stimulation, with pseudo-stimulation serving as the control group. The changes of multi-scale intrinsic fuzzy entropy (MIFE) of EEG signals before and after stimulation were compared. The results revealed that MIFE was significantly greater in the frontal and central regions after bipolar-stimulation ( P< 0.05), in the left central region after anodal-stimulation ( P< 0.05), and in the frontal and right central regions after cathodal-stimulation ( P< 0.05) in patients with left-hemisphere lesions. MIFE was significantly greater in the frontal, central and parieto-occipital joint regions after bipolar-stimulation ( P< 0.05), in the left frontal and right central regions after anodal- stimulation ( P< 0.05), and in the central and right occipital regions after cathodal-stimulation ( P< 0.05) in patients with right-hemisphere lesions. However, the difference before and after pseudo-stimulation was not statistically significant ( P> 0.05). The results of this paper showed that the bipolar stimulation pattern affected the largest range of brain areas, and it might provide a reference for the clinical study of rehabilitation after stroke.
