Research progress on Piperis Longi Fructus and predictive analysis of its quality markers.
10.19540/j.cnki.cjcmm.20220307.201
- Author:
Cui-Ping LIAO
1
;
Sha-Sha GE
1
;
Chaolumen ARATAN
2
;
Ya GAO
1
;
Ya TU
3
Author Information
1. Experimental Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Mongolian Medical College, Inner Mongolia Minzu University Tongliao 028000, China.
3. the Development of Chinese Medicine Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Piperis Longi Fructus;
chemical component;
pharmacological effect;
quality marker(Q-marker)
- MeSH:
Fruit/chemistry*;
Drugs, Chinese Herbal/analysis*;
Biomarkers/analysis*;
Piper
- From:
China Journal of Chinese Materia Medica
2022;47(19):5182-5192
- CountryChina
- Language:Chinese
-
Abstract:
Piperis Longi Fructus, made from the mature and immature fruit spikes of Piper longum, is a commonly used Mongolian medicine. In recent years, researchers have gradually deepened the research on ethnic medicines and found that Piperis Longi Fructus has significant effects in adjusting blood lipids and anti-cancer. Its new chemical components and pharmacological activities are also constantly updated. Subsequently, the development and application of Piperis Longi Fructus have attracted extensive attention. Thus, it is quite urgent to establish and improve a quality evaluation system for the medicine. On the basis of summarizing the chemical components and pharmacological effects of Piperis Longi Fructus and understanding the new concept of quality marker(Q-marker), the components which can be used as its Q-markers were analyzed from the aspects of the genetic relationship, traditional medicinal effects and properties, rules of compounding and compatibility, absorbed components and testability. The research can provide reference for the establishment of a quality evaluation system for Piperis Longi Fructus.
