Research progress in chemical constituents, pharmacological activity, and quality markers of Bruceae Fructus.
10.19540/j.cnki.cjcmm.20220604.201
- Author:
Shui-Yu XU
1
;
Yi-Xue ZHUANG
1
;
Zhi-Lai ZHAN
2
;
Cheng-Zi YANG
3
Author Information
1. College of Pharmacy, Fujian University of Traditional Chinese Medicine Fuzhou 350122, China.
2. National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
3. College of Pharmacy, Fujian University of Traditional Chinese Medicine Fuzhou 350122, China Fujian Quality Monitoring and Technology Service Center for Chinese Materia Medica Raw Material Fuzhou 350122, China.
- Publication Type:Journal Article
- Keywords:
Bruceae Fructus;
chemical constituent;
pharmacological activity;
quality marker(Q-marker);
resource distribution
- MeSH:
Fruit;
Drugs, Chinese Herbal/pharmacology*;
Quassins;
Flavonoids;
Biomarkers
- From:
China Journal of Chinese Materia Medica
2022;47(19):5158-5170
- CountryChina
- Language:Chinese
-
Abstract:
Bruceae Fructus is a Chinese herbal medicine with the chemical constituents mainly including Brucea javanica oil, quassinoids, flavonoids, steroids, triterpenoids, and alkaloids. Modern research demonstrates that Bruceae Fructus has anti-tumor, anti-malaria, anti-inflammatory, and lipid-lowering activities. This paper introduces the resource distribution, chemical constituents, and pharmacological activities of Bruceae Fructus. Further, according to the concept of quality marker(Q-marker), this paper predicts the Q-markers of Bruceae Fructus from the specificity of chemical components, pharmaceutical activity, measurability of chemical constituents, compatibility, and clinical efficacy, aiming to provide a theoretical basis for establishing the quality standard of Bruceae Fructus.
