Modernization of Chinese medicine Salviae Miltiorrhizae Radix et Rhizoma: a review.
10.19540/j.cnki.cjcmm.20220808.101
- Author:
Xiao-Jing MA
1
;
Jian YANG
1
;
Gui-Rong MA
2
;
Wen ZENG
1
;
Juan GUO
1
;
Ying MA
1
Author Information
1. State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Dongzhimen Hospital, Beijing University of Chinese Medicine Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
Salvia miltiorrhiza genome;
Salviae Miltiorrhizae Radix et Rhizoma;
salvianolic acids;
synthetic biology;
tanshinones
- MeSH:
Medicine, Chinese Traditional;
Salvia miltiorrhiza/chemistry*;
Drugs, Chinese Herbal/chemistry*;
Rhizome/chemistry*;
Plant Roots
- From:
China Journal of Chinese Materia Medica
2022;47(19):5131-5139
- CountryChina
- Language:Chinese
-
Abstract:
Modernization of Chinese medicine is an important development direction of traditional Chinese medical sciences. It is of great significance to understand the mechanism of Chinese medicine with basic research, which can also accelerate the development and utilization of Chinese medicine. Salviae Miltiorrhizae Radix et Rhizoma is one of the most commonly used Chinese medicines in China for the prevention and treatment of cardiovascular and cerebrovascular diseases. It has received key and extensive attention worldwide in the following aspects: main active ingredients and their pharmacological mechanism, function and regulation of their biosynthetic pathway and application of their synthetic biology as well as the clinical preparations. The new and developing chemical analysis, network pharmacology, molecular pharmacognosy and omics make the modernization research of Salviae Miltiorrhizae Radix et Rhizoma comprehensive and in-depth. This study systematically reviewed the modernization research of Salviae Miltiorrhizae Radix et Rhizoma, which focused on its pharmacological effects, preparation research, biosynthesis and regulation mechanism of the active ingredients, and expected to exert the model role of Salviae Miltiorrhizae Radix et Rhizoma in the research of Chinese medicine.
