Research progress on processing history evolution, chemical constituents, and pharmacological effects of Hirudo.
10.19540/j.cnki.cjcmm.20220411.201
- Author:
Qiu JIANG
1
;
Ling-Na WANG
1
;
Qian LIU
1
;
Chun-Miao YANG
1
;
Yong-Qing ZHANG
1
Author Information
1. School of Pharmacy, Shandong University of Traditional Chinese Medicine Ji'nan 250355, China.
- Publication Type:Journal Article
- Keywords:
Hirudo;
chemical constituent;
pharmacological effect;
processing history evolution
- MeSH:
Animals;
Drugs, Chinese Herbal/pharmacology*;
Evolution, Chemical;
Leeches;
Thrombosis;
Restraint, Physical
- From:
China Journal of Chinese Materia Medica
2022;47(21):5806-5816
- CountryChina
- Language:Chinese
-
Abstract:
As a traditional animal drug, Hirudo is slightly toxic and has the effects of breaking blood stasis, dredging meridians, expelling stasis, and resolving mass. It has a long history of processing, and the early boiling records can be traced back to the Han Dynasty. More than ten processing methods such as frying, roasting, and lime processing appeared later. After processing, Hirudo is deodorized and modified in taste and becomes crispy, which is conducive to crushing and clinical application. At present, the reported components in Hirudo mainly include protein polypeptides, pteridines, and lipids, which have anti-coagulant, anti-thrombotic, anti-atherosclerotic, anti-tumor, and other pharmacological effects. This study reviewed the processing history evolution, chemical consti-tuents, and pharmacological effects of Hirudo to provide a reference for the related research on Hirudo.
