Research progress and innovation of drug delivery devices based on children's multidimensional demand for medication.
10.19540/j.cnki.cjcmm.20220527.602
- Author:
Yu-Shan LENG
1
;
Yan-Jun YANG
1
;
Mao-Mao ZHU
1
;
Bing YANG
1
;
Liang FENG
1
;
Xiao-Bin JIA
1
Author Information
1. State Key Laboratory of Natural Medicine Active Components and Pharmacodynamics, School of Traditional Chinese Pharmacy, China Pharmaceutical University Nanjing 211198, China.
- Publication Type:Journal Article
- Keywords:
drug delivery devices;
medication;
special needs
- MeSH:
Child;
Humans;
Pharmaceutical Preparations;
Medicine, Chinese Traditional;
Drug Delivery Systems;
China
- From:
China Journal of Chinese Materia Medica
2022;47(21):5689-5699
- CountryChina
- Language:Chinese
-
Abstract:
Pediatric medication in China is characterized by a lack of child-specific drugs and insufficient types, specifications, dosage forms, and delivery devices. In recent years, new dosage forms with good compliance, such as inhalation preparation, rectal delivery system, and transdermal delivery system, have attracted more attention in pediatric medication. Because of the physiological characteristics of delicate viscera, difference in swallowing ability and psychological characteristics of fear of pain and aversion to bitter taste, it is particularly important to select suitable drug delivery route and drug delivery device according to children's physiological characteristics. With the help of the special drug delivery devices, traditional Chinese medicine and innovative Chinese medicine can be administered according to the expected design path, and drug delivery devices can ensure the accurate dose and improve the complia-nce to achieve the purpose of effective and safe drug delivery. It is also a way to realize the re-innovation of traditional Chinese medicine. The present study summarized the research progress in drug delivery devices for common drug delivery routes and new drug deli-very routes, put forward the innovative design idea of children's drug delivery devices according to the special needs of children, poin-ted out the compatibility of drug delivery devices and other problems in the current development, and prospected the application of intelligent information technology and additive manufacturing technology in drug delivery device innovation. This is expected to provide references for the development of innovative drugs and drug delivery devices suitable for children's multidimensional demand for medication.
