Quality evaluation of Psoraleae Fructus based on QAMS method and TLC identification.
10.19540/j.cnki.cjcmm.20220421.202
- Author:
Dan-Ni WANG
1
;
Jia-Ming GUO
1
;
Xin CHAI
1
;
Jing YANG
1
;
Yue-Fei WANG
1
Author Information
1. Tianjin Key Laboratory of TCM Chemistry and Analysis, State Key Laboratory of Component-based Chinese Medicine,Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine Tianjin 301617, China.
- Publication Type:Journal Article
- Keywords:
Psoraleae Fructus;
TLC identification;
quality control;
quantitative analysis of multi-components by single marker(QAMS)
- MeSH:
Chromatography, High Pressure Liquid/methods*;
Drugs, Chinese Herbal/analysis*;
Ficusin;
Fruit/chemistry*;
Furocoumarins/analysis*;
Psoralea
- From:
China Journal of Chinese Materia Medica
2022;47(15):4089-4097
- CountryChina
- Language:Chinese
-
Abstract:
The present study established a determination method of Psoraleae Fructus by quantitative analysis of multi-components by the single marker(QAMS) and further improved the thin-layer chromatography(TLC) method. The QAMS method was established by UPLC with psoralen as the internal marker, and the content of psoralenoside, isopsoralenoside, psoralen, and isopsoralen was simultaneously determined. As revealed by the comparison with results of the external standard method, the QAMS method was accurate and feasible. According to the current quality standards of Psoraleae Fructus, the TLC method was further optimized and improved, and bakuchiol was added for identification based on the original TLC method with psoralen and isopsoralen as indicators. This study provides a reference for improving the quality control method of Psoraleae Fructus.
