Research Progress in Circadian Rhythm and Arrhythmia.
10.3881/j.issn.1000.503X.14205
- Author:
Jin-Feng SU
1
;
Fan YANG
1
;
Li DENG
1
Author Information
1. Department of Cardiac Function Room,Jingmen Second People's Hospital,Jingmen,Hubei 448000,China.
- Publication Type:Journal Article
- Keywords:
arrhythmia;
biological clock;
brain and muscle Arnt-like protein 1;
circadian locomotor output cycles kaput;
circadian rhythm
- MeSH:
Humans;
Circadian Rhythm/genetics*;
Myocytes, Cardiac;
Arrhythmias, Cardiac
- From:
Acta Academiae Medicinae Sinicae
2022;44(5):919-922
- CountryChina
- Language:Chinese
-
Abstract:
Studies have demonstrated that the occurrence of a variety of arrhythmias presents an obvious circadian rhythm,which may be regulated by circadian rhythm genes.Circadian cycle and light stimulation can affect circadian rhythm genes and proteins,which constitute a transcription-translation loop that can regulate the ion channels in myocardial cell membrane through nervous-humoral regulation and changes in central clock-sub-clock gene expression,thereby modulating arrhythmia.This article reviews the molecular basis,mechanism,and performance of circadian rhythm in regulating arrhythmia.
