Research Progress in Mechanism of Lipid Nephrotoxicity.
10.3881/j.issn.1000.503X.14243
- Author:
Shuo KANG
1
;
Xuan ZHANG
1
Author Information
1. Department of Nephrology,Tianjin Children's Hospital,Tianjin 300204,China.
- Publication Type:Journal Article
- Keywords:
NF-κB;
autophagy;
ectopic fat deposition;
lipidnephrotoxicity;
nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome
- MeSH:
Oxidative Stress;
Autophagy;
Endoplasmic Reticulum Stress;
Kidney;
Lipids
- From:
Acta Academiae Medicinae Sinicae
2022;44(5):914-918
- CountryChina
- Language:Chinese
-
Abstract:
Dyslipidemia can damage a variety of organs including kidney.The mechanisms of lipid-induced kidney injury include autophagy defects,oxidative stress,endoplasmic reticulum stress,inflammation,and epigenetic modification.This article reviews recent research progress in this field.